RNA processing errors triggered by cadmium and integrator complex disruption are signals for environmental stress
Abstract Background Adaptive responses to stress are essential for cell and organismal survival.In metazoans, little is known about the impact of environmental stress on RNA homeostasis.Results By studying the regulation of a cadmium-induced gene named numr-1 in Caenorhabditis elegans, we discovered that disruption of RNA processing acts as a signa